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• Discontinue GLUCOVANCE if the patient’s eGFR later falls below 30 mL/minute/1. Difference between glucovance and metformin, glucovance tablet uses, glucophage glucovance, glucovance mims malaysia. 5 mg glyburide with 500 mg metformin hydrochloride, and 5 mg glyburide with 500 mg metformin hydrochloride. 5mg/500mg tablet is composed of Glibenclamide (2. • In patients taking GLUCOVANCE whose eGFR later falls below 45 mL/min/1. 5mg) Metformin (500mg) This medicine in combination with an appropriate diet and exercise, is used for treating type 2 diabetes mellitus (condition characterized by elevated sugar levels). CONTRAINDICATIONS GLUCOVANCE is contraindicated in patients with:. In addition, each tablet contains the following inactive ingredients: microcrystalline cellulose, povidone, croscarmellose sodium, and magnesium stearate. 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